Home

About

Publications

Science

Contact

Computational Chemistry Resource

Molecular Design Consultancy for Drug Discovery

Patents

Click here for Google Patents Search

Inhibitor of p38 MAP kinase Filed 31 Aug 2016 - Issued 18 Apr 2017 - Alistair Ian Longshaw - Respivert Ltd. John King-Underwood: Jennifer Venable .... 2006, 149, 393-404) as well as in various in vivo animal models (Underwood, D. C. et al., ...

Aromatic heterocyclic compounds as antiinflammatory compounds App. - Filed 13 Feb 2015 - Published 21 Dec 2016 - Alistair Ian Longshaw - Respivert Limited John King-Underwood: Jennifer Diane Venable ...

Pyrazolyl-ureas as kinase inhibitors App. - ? Filed 13 Feb 2015 - ?Published 21 Dec 2016 - ?Alistair Ian Longshaw - ?Respivert Limited ... King-Underwood: Jennifer Diane Venable .... 2006, 149:393-404) as well as in various in vivo animal models (Underwood, D.C. et al., Am. ...... Peter G.M. Wuts, published by John Wiley & Sons Inc; 4 th Rev Ed., 2006, ISBN-10: 0471697540. ?Overview · ?Related · ?Discuss

INHIBITOR OF p38 MAP KINASE www.google.co.uk/patents/US20150232450 App. - ? Filed 13 Feb 2015 - Published 20 Aug 2015 - Alistair Ian Longshaw - Respivert Ltd John King-Underwood: Jennifer Venable

Novel compounds App. - Filed 13 Feb 2015 - Published 2 Mar 2017 - Alistair Ian Longshaw - Respivert Limited Inventor: Alistair Ian Longshaw: Euan Alexander Fraser Fordyce: Stuart Thomas Onions: John King-Underwood: Jennifer Diane Venable ...

,

Novel 5,6-Dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivatives Inventor: FORDYCE EUAN ALEXANDER FRASER [GB] HUNT SIMON FRASER [GB] (+7) Applicant: PULMOCIDE LTD [GB] CPC: A61K31/55 A61K45/06 C07D495/04 (+1) IPC: A61K31/55 A61K45/06 C07D519/00 Publication info: US2017355718 (A1) 2017-12-14 Priority date: 2014-12-18

  QUINAZOLIN-4 (3H) -ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS Inventor: KING-UNDERWOOD JOHN [GB] ITO KAZUHIRO [GB] (+4) Applicant: RESPIVERT LTD [GB] CPC: A61K31/519 C07D487/04 IPC: A61K31/519 A61P11/00 A61P11/06 (+4) Publication info: CY1116315 (T1) 2017-02-08 Priority date: 2010-10-18

COMPOUNDS Inventor: KING-UNDERWOOD JOHN [GB] ITO KAZUHIRO [GB] (+4) Applicant: RESPIVERT LTD [GB] CPC: C07D487/04 IPC: A61K31/519 A61P11/00 A61P11/06 (+4) Publication info: CY1116057 (T1) 2017-02-08 Priority date: 2009-10-19

P38 MAPK KINASE INHIBITOR Inventor: ITO KAZUHIRO [GB] STRONG PETER [GB] (+6) Applicant: RESPIVERT LTD [GB] CPC: C07D401/12 IPC: A61K31/415 A61P11/00 A61P29/00 (+1) Publication info: CY1114665 (T1) 2016-10-05 Priority date: 2008-10-02

PYRAZOLYL-UREAS AS KINASE INHIBITORS. Inventor: WALTERS IAIN [GB] KING-UNDERWOOD JOHN (+4) Applicant: RESPIVERT LTD [GB] CPC: A61K31/497 A61K31/498 A61K31/5377 (+7) IPC: A61K31/506 C07D401/14 C07D409/14 (+3) Publication info: MX2016010571 (A) 2017-01-05 Priority date: 2014-02-14

  1-PYRAZOLYL-3-(4-((2-ANILINOPYRIMIDIN-4 -YL) OXY) NAPTHTHALEN-1 - YL) UREAS AS P38 MAP KNASE INHIBITORS Inventor: ITO KAZUHIRO [GB] CHARRON CATHERINE ELISABETH [GB] (+3) Applicant: RESPIVERT LTD [GB] CPC: A61K2300/00 (+9) IPC: A61K31/506 A61K9/00 Publication info: US2017007604 (A1) 2017-01-12 Priority date: 2011-10-03

1-PYRAZOLYL-3-(4-((2-ANILINOPYRIMIDIN-4-YL)OXY)NAPTHTHALEN-1-YL)UREAS AS P38 MAP KINASE INHIBITORS Inventor: ITO KAZUHIRO [GB] CHARRON CATHERINE ELISABETH [GB] (+6) Applicant: CPC: A61K31/215 A61K31/351 A61K31/4155 (+5) IPC: A61K31/4155 A61K31/506 C07D403/12 (+1) Publication info: PL2763984 (T3) 2016-10-31 Priority date: 2011-10-03

P38MAP KINASE INHIBITOR Inventor: ITO KAZUHIRO RAPEPORT WILLIAM GARTH (+6) Applicant: RESPIVERT LTD [GB] CPC: A61K31/24 A61K31/351 A61K31/4439 (+1) IPC: A61K A61P C07D Publication info: ZA201108048 (B) 2013-04-24 Priority date: 2009-04-03

P38 MAP KINASE INHIBITORS Inventor: ITO KAZUHIRO RAPEPORT WILLIAM GARTH (+8) Applicant: RESPIVERT LTD [GB] CPC: C07D401/12 C07D401/14 C07D403/12 IPC: A61K A61P C07D Publication info: ZA201103180 (B) 2012-10-31 Priority date: 2008-10-02

NOVEL COMPOUNDS Inventor: KING-UNDERWOOD JOHN [GB] HARDY GEORGE [GB] (+3) Applicant: RESPIVERT LTD [GB] CPC: C07D401/12 C07D401/14 C07D403/12 IPC: C07D401/12 C07D401/14 C07D403/12 Publication info: US2016130256 (A1) 2016-05-12 Priority date: 2010-04-01

Novel Compounds Inventor: KING-UNDERWOOD JOHN [GB] KAZUHIRO ITO [GB] (+6) Applicant: RESPIVERT LTD [GB] CPC: C07D401/12 IPC: C07D401/12 Publication info: US2016115152 (A1) 2016-04-28 Priority date: 2010-04-08

PYRAZOLYL-UREAS AS KINASE INHIBITORS. Inventor: FYFE MATTHEW COLIN THOR [GB] ITO KAZUHIRO (+10) Applicant: RESPIVERT LTD [GB] CPC: A61K31/506 A61K31/5377 A61K45/06 (+5) IPC: A61K31/4155 A61K31/506 A61P11/00 (+5) Publication info: MX2015002044 (A) 2016-01-22 Priority date: 2012-08-17

inibidor de quinase p38map. Inventor: CHARRON CATHERINE ELISABETH [GB] KING-UNDERWOOD JOHN [GB] (+6) Applicant: RESPIVERT LTD [GB] CPC: IPC: A61K31/415 A61P11/00 A61P29/00 (+1) Publication info: BRPI1014868 (A2) 2016-04-12 Priority date: 2009-04-03

4,5-DIHYDRO-6H-THIENO[3,2-D]BENZAZEPINE DERIVATIVES AND THEIR USE TO TREAT RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTIONS Inventor: FORDYCE EUAN ALEXANDER FRASER [GB] HUNT SIMON FRASER [GB] (+7) Applicant: PULMOCIDE LTD [GB] CPC: C07D495/04 IPC: A61K31/55 A61P11/00 C07D495/04 Publication info: WO2016097761 (A1) 2016-06-23 Priority date: 2014-12-18

PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS Inventor: DUFFY LORNA ANNE [GB] KING-UNDERWOOD JOHN [GB] (+7) Applicant: RESPIVERT LTD [GB] TOPIVERT PHARMA LTD [GB] CPC: A61K31/506 A61K31/5377 C07D401/14 (+6) IPC: A61K31/506 A61K31/5377 C07D401/14 (+6) Publication info: US2015203475 (A1) 2015-07-23 US9249125 (B2) 2016-02-02 Priority date: 2012-08-29

  p38 MAP KINASE INHIBITOR Inventor: ITO KAZUHIRO PETER STRONG (+7) Applicant: RESPIVERT LTD CPC: C07D401/12 C07D401/14 C07D403/12 IPC: C07D401/12 C07D401/14 C07D403/12 (+2) Publication info: JP2015013890 (A) 2015-01-22 JP5959587 (B2) 2016-08-02 Priority date: 2008-12-11

  1-PIRAZOLIL-3-(4-((2-ANILINOPIRIMIDIN-4-IL)OXI)NAFTALEN-1-IL)UREAS COMO INHIBIDORES DE PROTEÍNAS CINASAS ACTIVADAS POR MITÓGENO P38 Inventor: ITO KAZUHIRO CHARRON CATHERINE ELISABETH (+6) Applicant: RESPIVERT LTD [GB] CPC: IPC: A61K31/4155 A61K31/506 C07D403/12 (+1) Publication info: CR20140192 (A) 2014-07-22 Priority date: 2011-10-03

Therapeutic uses Inventor: KING-UNDERWOOD JOHN [GB] ITO KAZUHIRO [JP] (+7) Applicant: RESPIVERT LTD [GB] CPC: A61K31/415 IPC: A61K31/4439 A61K31/4965 A61K31/5377 (+4) Publication info: TW201130813 (A) 2011-09-16 Priority date: 2009-12-11

Novel compound Inventor: ITO KAZUHIRO [JP] CHARRON CATHERINE ELISABETH [CA] (+6) Applicant: RESPIVERT LTD [GB] CPC: IPC: A61K31/506 C07D403/12 A61P11/00 (+2) Publication info: TW201319058 (A) 2013-05-16 TWI560186 (B) 2016-12-01 Priority date: 2011-10-03

  P38 MAP Kinase Inhibitors Inventor: KING-UNDERWOOD JOHN [GB] MURRAY PETER JOHN [GB] (+3) Applicant: KING-UNDERWOOD JOHN [GB] MURRAY PETER JOHN [GB] (+3) CPC: C07D401/12 C07D401/14 C07D405/14 (+1) IPC: A61K31/4439 A61K31/444 A61K31/496 (+21) Publication info: US2013040962 (A1) 2013-02-14 US9024041 (B2) 2015-05-05 Priority date: 2010-04-08

  Novel compounds Inventor: ITO KAZUHIRO [JP] STRONG PETER [GB] (+7) Applicant: RESPIVERT LTD [GB] CPC: IPC: A61K31/4439 A61K31/5377 C07D401/10 (+4) Publication info: TW201111360 (A) 2011-04-01 Priority date: 2009-07-17

  1,2,4-Oxadiazole derivatives as GPCR receptor agonists Inventor: FYFE MATTHEW KING-UNDERWOOD JOHN (+5) Applicant: PROSIDION LTD CPC: C07D401/14 C07D413/04 C07D413/06 (+3) IPC: C07D401/14 C07D413/04 C07D413/06 (+4) Publication info: NZ547965 (A) 2009-12-24 Priority date: 2003-12-24

AMINOHETEROARYL COMPOUNDS AS FOR THE TREATMENT OF DISEASES MEDIATED BY C-MET KINASE ACTIVITY Inventor: DRUMMOND ALAN HASTINGS [GB] KING-UNDERWOOD JOHN [GB] (+3) Applicant: CHROMA THERAPEUTICS LTD [GB] DRUMMOND ALAN HASTINGS [GB] (+4) CPC: C07D401/04 C07D401/14 IPC: A61K31/4439 A61P35/00 C07D401/04 (+1) Publication info: WO2008053157 (A1) 2008-05-08 Priority date: 2006-10-31

Papers

Cystic Fibrosis

Chem Biol 2013 Jul;20(7):943-55

COPD

J. Med. Chem., 2016, 59 (5), pp 1727–1746

PUR1800

Respiratory Syncytial Virus (RSV)

Bioorg Med Chem Letts, Vol 27 (10), 15 May 2017, p2201-2206

Project reaches FIH

Apserguillus Infection

Antimicrob Agents Chemother 2017 May 24;61(5). Epub 2017 Apr 24.

Project reaches FIH

Other

Chapter on AutoTaxin

Home

About

Publications

Science

Contact