John King-Underwood
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Computational Chemistry Resource is a Consultancy Business specialising in supporting Medicinal Chemistry projects using Molecular Modelling, Structure Based Design, Virtual Screening and Informatics.
It was formed in 2003 by john king-underwood as a spin-out from OSI Pharmaceuticals. Initially specialising in providing onsite Molecular Modelling and Informatics support to small companies, spinouts and virtual screening service providers, in the biotech sector, it now has it’s own infrastructure of software and hardware in order to provide a full service.
It has successfully supported customers through Hit Finding, Hit2Lead and Lead Optimisation projects.
4 of which have resulted in clinical candidates.
The projects that have been supported include Kinases, GPCRs, Nuclear Receptors, enzymes and many others across many areas of drug discovery such as Cancer, Respiratory Disease, Diabetes and Infectious Disease.
Customers have included Respivert, Pulmocide, 448T, Karus Therapeutics, Chroma Therapeutics, Inhibox and Sygnature Chemical Services. .